Reviews on PEG-coated liposomal drug carriers.
نویسندگان
چکیده
منابع مشابه
Novel PEG-coated niosomes based on bola-surfactant as drug carriers for 5-fluorouracil.
Innovative niosomes made up of α,ω-hexadecyl-bis-(1-aza-18-crown-6) (bola), Span 80® and cholesterol (2:5:2 molar ratio) are proposed as suitable delivery systems for the administration of 5-fluorouracil (5-FU), an antitumoral compound largely used in the treatment of breast cancer. The bola-niosomes, after sonication procedure, showed mean sizes of ~200 nm and a loading capacity of ~40% with r...
متن کاملPolyethylene glycol (PEG) labeled liposomal drug delivery systems as a source for dynamic absolute MR thermometry
R. Deckers, S. M. Sprinkhuizen, B. J. Crielaard, J. H. Ippel, R. Boelens, T. Lammers, C. J. Bakker, and L. W. Bartels Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands, Department of Pharmaceutics, Utrecht University, Utrecht, Netherlands, Department of NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands, Departmen...
متن کاملPulmonary delivery of insulin by liposomal carriers.
Growing attention has been given to the potential of a pulmonary route as a non-invasive administration for systemic delivery of therapeutic agents (mainly peptides and proteins). The lungs provide a large absorptive surface area, extremely thin absorptive mucosal membrane, and good blood supply. The non-invasive nature of this pathway makes it especially valuable for the delivery of large mole...
متن کاملWhole blood coagulation on protein adsorption-resistant PEG and peptide functionalised PEG-coated titanium surfaces.
The aim of this study was to investigate whole blood coagulation on low blood plasma protein adsorbing surfaces. For this purpose, the polycationic graft copolymer poly(L-lysine)-g-poly(ethylene glycol) (PLL-g-PEG), PLL-g-PEG grafted with a cell adhesive peptide containing the amino acid sequence -Arg-Gly-Asp- (RGD), and PLL-g-PEG with a control peptide -Arg-Asp-Gly- (RDG) were adsorbed onto ti...
متن کاملBiodegradable tetra-PEG hydrogels as carriers for a releasable drug delivery system.
We have developed an approach to prepare drug-releasing Tetra-PEG hydrogels with exactly four cross-links per monomer. The gels contain two cleavable β-eliminative linkers: one for drug attachment that releases the drug at a predictable rate, and one with a longer half-life placed in each cross-link to control biodegradation. Thus, the system can be optimized to release the drug before signific...
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ژورنال
عنوان ژورنال: Drug Delivery System
سال: 2001
ISSN: 1881-2732,0913-5006
DOI: 10.2745/dds.16.165